Top Quality Epidermal Growth Factor (EGF) 1,000,000IU/vial
Purity (HPLC): 99.0%min.
Appearance: White lyophilized powder
Storage:Stored at 20 degrees below zero.
Human EGF is a 6045-Da protein with 53 amino acid residues and three intramolecular disulfide
bonds Epidermal growth factor or EGF is a growth factor that plays an important role in the regulation
of cell growth, proliferation, and differentiation by binding to its receptor EGFR. Human EGF is a
6045-Da protein with 53 amino acid residues and three intramolecular disulfide bonds.
The discovery of EGF won Stanley Cohen of Vanderbilt University a Nobel Prize in Physiology and
Medicine in 1986 and was patented for cosmetic use by Greg Brown in 1989.
EGF results in cellular proliferation, differentiation, and survival. EGF is a low-molecular-weight
polypeptide first purified from the mouse submandibular gland, but since then found in many human
tissues including submandibular gland, parotid gland. Salivary EGF, which seems also regulated by
dietary inorganic iodine, also plays an important physiological role in the maintenance of oro-esophageal and gastric tissue integrity. The biological effects of salivary EGF include healing of oral and gastro esophageal ulcers, inhibition of gastric acid secretion, stimulation of DNA synthesis as well as
mucosal protection from intraluminal injurious factors such as gastric acid, bile acids, pepsin, and
trypsin and to physical, chemical and bacterial agents.
Epidermal growth factor can be found in human platelets, macrophages, urine, saliva, milk, and plasma.
JUST for R&D Research Lab use,not for Human use or Commercial sale
|Product Name||EGF||CAS NO||62253-63-8|
|Molecular Formula||Molecular Weight||6.2kD|